Original article
Size-controlled green synthesis of silver nanoparticles mediated by gum ghatti (Anogeissus latifolia) and its biological activity
1 National Centre for Compositional Characterisation of Materials (NCCCM), Bhabha Atomic Research Centre, ECIL PO, Hyderabad, 500 062, AP, India
2 Department of Biochemistry, University College of Science, Osmania University, Hyderabad, 500 007,, AP, India
Organic and Medicinal Chemistry Letters 2012, 2:17 doi:10.1186/2191-2858-2-17
Published: 9 May 2012Abstract
Background
Gum ghatti is a proteinaceous edible, exudate tree gum of India and is also used in traditional medicine. A facile and ecofriendly green method has been developed for the synthesis of silver nanoparticles from silver nitrate using gum ghatti (Anogeissus latifolia) as a reducing and stabilizing agent. The influence of concentration of gum and reaction time on the synthesis of nanoparticles was studied. UV–visible spectroscopy, transmission electron microscopy and X-ray diffraction analytical techniques were used to characterize the synthesized nanoparticles.
Results
By optimizing the reaction conditions, we could achieve nearly monodispersed and size controlled spherical nanoparticles of around 5.7 ± 0.2 nm. A possible mechanism involved in the reduction and stabilization of nanoparticles has been investigated using Fourier transform infrared spectroscopy and Raman spectroscopy.
Conclusions
The synthesized silver nanoparticles had significant antibacterial action on both the Gram classes of bacteria. As the silver nanoparticles are encapsulated with functional group rich gum, they can be easily integrated for various biological applications.
