Table 4

Three component Strecker reaction using amines (1 mmol), carbonyl compounds (1 mmol) and TMSCN (1.2 mmol) in water in presence of indium (10 mol%)

Entry

Amine

Carbonyl compound

Product

Time (min)

Yield (%)^a

Ref.

1

30

98

[11]

2

75

93

[15]

3

75

79

[11]

4

45

86

[11]

5

60

88

[11]

6

75

91

[11]

7

90

94

[21]

8

75

95

[21]

9

90

97

[21]

10

45

98

[10]

^aisolated yield

Bandyopadhyay et al. Organic and Medicinal Chemistry Letters 2011 1:11   doi:10.1186/2191-2858-1-11